Saturday , April 17 2021

Japanese researchers transplant stem cells into the brain to treat Parkinson's disease



Stem cells of Parkinson's disease

Stem cells transplanted into the brain toward Parkinson's & nbsp | & nbspPhoto Photos: & nbspView

Tokyo: Japanese researchers said on Friday that they had transplanted stem cells into the brain of the patient in the first stage of an innovative experiment to treat Parkinson's disease. The research team at Kyoto University injected the induced Pluripotent Stem (iPS) cells that could develop into any cell in the body, into the brain of a male patient in the 1950s, the University announced in a press release.

The man was stable after the operation, which was carried out last month, and will now be followed by two years, the university adds. Researchers injected 2.4 million iPS cells on the left side of the patient, in an operation lasting about three hours.

If problems are not observed over the next six months, they will implant 2.4 million cells to the right. IPS cells from healthy donors are developed into dopamine dopamine precursors, which are no longer present in Parkinson's disease patients.

The operation came after the University announced in July that it would conduct a trial with seven participants between the ages of 50 and 69. The first is a procedure involving the insertion of stem cells into the brain to treat Parkinson's disease.

"I value patients to participate in the trial with courage and determination," Jun Takahashi, a professor from Kyoto University, told reporters on Friday, according to NHK's public television.

Parkinson's disease is a chronic, degenerative neurological disorder that affects the motor body system, often causing shakes and other difficulty in movement. In the world, about 10 million people have a disease, according to Parkinson's disease.

Currently available therapies "improve the symptoms without slowing down or stopping progression of the disease," says the Foundation. The human trial comes after an early trial with the monkeys.

Researchers last year reported that receiving Parkinson's symptoms again had significant mobility after iPS cells were inserted into the brain.

They also confirmed that iPS cells were not transformed into tumors for two years after implantation. iPS cells are generated by stimulating mature, already specialized cells back into juvenile status – basically cloning without the need for an embryo.

Cells can be transformed into a variety of cell types, and their use is a key sector of medical research.


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